AJOVY prefilled syringe migraine injection instructions

How to use the AJOVY prefilled syringe

Watch the video below or scroll down for step-by-step instructions. Follow these directions whether you take AJOVY quarterly or monthly.

You can use the prefilled syringe by yourself at home, or have it administered by your healthcare provider in their office. AJOVY also comes in an easy-to-use autoinjector. For instructions on how to use the autoinjector, click here.

Step-by-step prefilled syringe instructions

To prepare for your injection, take your prefilled syringe out of the refrigerator. Make sure to wait at least 30 minutes for it to reach room temperature. Now you’re ready to follow the steps below:

Step 1:

Pick up the syringe

Pick up the body of the prefilled syringe with one hand and pull the needle cap straight off with your other hand. Do not shake or twist. Throw cap away immediately.

AJOVY prefilled syringe instructions step 1

Step 2:

Select and prepare
injection site

Choose an injection area, such as on your stomach, front of thighs, or back of upper arms. Clean the area with an alcohol swab.

AJOVY prefilled syringe instructions step 2

Step 3:

Insert the needle at a
45° to 90° angle

Use your free hand to gently pinch up at least 1 inch of the injection site. Carefully insert the needle into pinched skin at a 45° to 90° angle.

AJOVY prefilled syringe instructions step 3

Step 4:

Slowly push the plunger
all the way down

When the needle is all the way into your skin, use your thumb to slowly push the plunger down as far as it will go.

AJOVY prefilled syringe instructions step 4

Step 5:

Pull needle straight out, then
apply gauze or cotton ball

After you have injected all of the medicine, pull the needle straight out, then apply gauze or a dry cotton ball on the site for a few seconds.

AJOVY prefilled syringe instructions step 5

For more detailed steps on taking AJOVY using the prefilled syringe, make sure to read the full Instructions for Use.

Download full instructions for taking AJOVY prefilled syringe Read full instructions for use

Important things to know before injecting:

  • Before injecting, let AJOVY sit at room temperature for 30 minutes. Do not warm up using a heat source such as hot water or a microwave.
  • Keep AJOVY prefilled syringe out of the reach of small children.
  • After you remove the needle cap from AJOVY, to prevent infection, do not touch the needle.
  • DO NOT pull back on the plunger at any time as this can break the prefilled syringe.
  • DO NOT inject AJOVY in your veins (intravenously).
  • DO NOT re-use your AJOVY prefilled syringe as this could cause infection or injury.
  • DO NOT share your AJOVY prefilled syringe with another person. You may give another person an infection or get an infection from them.
  • You may give AJOVY yourself. You should not get your first dose of AJOVY until you or your caregiver receive training from a healthcare provider on the right way to use AJOVY.

How to Dispose Used Sharps: DO’s and DON’Ts

The AJOVY prefilled syringe is for single-time (one-time) use only. After use, put the prefilled syringe in an FDA-cleared sharps disposal container right away. DO NOT throw away your used sharps disposal container in your household trash.

Learn more by downloading our Sharps Disposal Brochure.

Download the sharps disposal brochureDownload Sharps Disposal Brochure 
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How to store and handle the AJOVY prefilled syringe

Make sure you’re familiar with storing and handling your AJOVY prefilled syringe before starting treatment. After injecting, you must take certain steps to ensure safe disposal of your used prefilled syringe.

  • Store AJOVY in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • Keep AJOVY in the carton it comes in to protect it from light.
  • If necessary, AJOVY may be kept in the original carton at room temperature up to 30°C (86°F) for a maximum of 7 days. After removal from the refrigerator, AJOVY must be used within 7 days or discarded. Once stored at room temperature, do not place back in the refrigerator.
  • DO NOT freeze. If AJOVY freezes, throw it away in a sharps disposal container.
  • Keep AJOVY out of extreme heat and direct sunlight.
  • DO NOT shake AJOVY.

Download and read the full storage and handling instructions before you start taking AJOVY.

Download full storage and handling instructions for AJOVY Download full Storage and Handling instructions