AJOVY Autoinjector instruction

Autoinjector instructions

Watch the video below or scroll down for step-by-step instructions. Follow these directions whether you take AJOVY quarterly or monthly.

AJOVY comes in an easy-to-use autoinjector.* You can use the autoinjector by yourself at home, or have it administered by your healthcare provider in their office. AJOVY also comes in a prefilled syringe. For instructions on how to use the prefilled syringe, click here.

*Two human factor studies assessed evaluators’ ability to complete critical tasks in order to demonstrate use of the AJOVY Autoinjector in simulated-use sessions. When asked “Was the autoinjector easy to use?”, 97% in study 1 (N=30) and 98% in study 2 (N=47) answered “Yes”.

AJOVY savings offer

Activate or get your savings offer.

start saving today
AJOVY sign up for updates

Sign up to get updates about AJOVY and more.


How to use the AJOVY Autoinjector

To prepare for your injection, take your autoinjector out of the refrigerator. Make sure to wait 30 minutes until it reaches room temperature. Now you’re ready to follow the steps below.

Step 1:

Uncap the autoinjector

With one hand, firmly pull the cap straight off the autoinjector (don’t twist) and throw the cap away immediately.

AJOVY Autoinjector instructions step 1

Step 2:

Place at a 90o angle

Place the autoinjector at a 90° angle against your skin at your chosen injection site.

AJOVY Autoinjector instructions step 2

Step 3:

Press down and hold autoinjector until 10 seconds after second click

Press down on the autoinjector. You will hear a click. This means the injection has started and you should see the blue plunger move down. You will hear a second click. Remove autoinjector 10 seconds after.

AJOVY Autoinjector instructions step 3

For more detailed steps on using the AJOVY Autoinjector, read the full Instructions for Use.

Download full instructions for taking AJOVY Autoinjector Read full instructions for use

Important things to consider

AJOVY Autoinjector is for single-time (one-time) use only. After use, put the autoinjector into an FDA-approved sharps disposal container right away. Do not throw away the sharps disposal container in your household trash.

Learn more by downloading our Sharps Disposal Brochure.

Download the sharps disposal brochure Download Sharps Disposal Brochure
  • Before injecting, let AJOVY sit at room temperature for 30 minutes. Do not warm up using a heat source such as hot water or a microwave.
  • Keep AJOVY Autoinjector out of the reach of small children.
  • After you remove the needle cap, to prevent infection, do not touch the needle.
  • Do not inject AJOVY in your veins (intravenously).
  • Do not reuse your AJOVY Autoinjector as this could cause infection or injury.
  • Do not share your AJOVY Autoinjector with another person. You may give another person an infection or get an infection from them.
  • You may give AJOVY yourself. If you feel uncomfortable, you should not get your first dose of AJOVY until you or your caregiver receive training from a healthcare provider on the right way to use AJOVY.
AJOVY Shared Solutions Nurse Assistance

Nurse assistance

Need help or have questions about taking AJOVY using the autoinjector? Don’t hesitate to contact our nurses who can help answer questions you may have. Call a Shared Solutions® Nurse at 1-800-887-8100, Monday–Friday, 8 AM–6 PM CT.

How to store and handle the AJOVY Autoinjector

  • Make sure to keep AJOVY in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze.
  • Keep AJOVY in the carton it comes in to protect from light.
  • If needed, AJOVY may be stored at room temperature between 68°F to 77°F (20°C to 25°C) in the carton it comes in for up to 24 hours. Do not use AJOVY if it has been out of the refrigerator for 24 hours or longer. Dispose of (throw away) AJOVY in a sharps disposal container if it has been out of the refrigerator for 24 hours or longer.
  • Do not freeze. If AJOVY freezes, throw it away in a sharps disposal container.
  • Keep AJOVY out of extreme heat and direct sunlight.
  • Do not shake AJOVY.

Download and read the full storage and handling instructions before you start taking AJOVY.

Download full storage and handling instructions for AJOVY Download full Storage and Handling instructions
AJOVY savings offer

Activate or get your savings offer.

start saving today
AJOVY sign up for updates

Sign up to get updates about AJOVY and more.